RESUMO
No disponible
Assuntos
Feminino , Humanos , Masculino , Anemia Perniciosa/complicações , Anemia Perniciosa/diagnóstico , Anemia Perniciosa/tratamento farmacológico , Ferritinas/uso terapêutico , Ferro/deficiência , Vitamina B 12/uso terapêutico , Transferrina/uso terapêutico , Eritropoese , Deficiência de Vitamina B 12/diagnóstico , Deficiência de Vitamina B 12/terapiaRESUMO
Acute sarcoid arthritis may be present in isolation or as part of Löfgren's syndrome. Its true incidence is unclear since the diagnosis may be difficult when patients present with articular symptoms alone. The diagnosis of sarcoid arthritis is based upon suggestive clinical, imaging, synovial fluid findings, and in some cases upon synovial biopsy. The finding of sterile noncaseating granulomatous inflammation on biopsy is supportive, but it is not pathognomic of sarcoidosis. On the other hand, sarcoidosis has been associated with autoimmune diseases, especially with autoimmune thyroid disease. We believe that it might be of interest to evaluate thyroid function testing in patients with clinical features consistent with sarcoid arthritis, and the diagnosis of sarcoidosis should be considered in patients who present with symmetrical arthritis and thyroid autoimmune disease. We describe herein a patient with subclinical autoimmune hypothyroidism and an acute symmetrical oligoarthritis, with a clinical presentation and laboratory data consistent with acute sarcoid arthritis (Ref. 14).
Assuntos
Artrite/diagnóstico , Doenças Autoimunes/complicações , Hipotireoidismo/complicações , Sarcoidose/diagnóstico , Doença Aguda , Adulto , Artrite/complicações , Humanos , Masculino , Sarcoidose/complicaçõesAssuntos
2-Piridinilmetilsulfinilbenzimidazóis/administração & dosagem , Antiulcerosos/administração & dosagem , Famotidina/administração & dosagem , Deficiência de Magnésio/induzido quimicamente , Omeprazol/efeitos adversos , Inibidores da Bomba de Prótons/efeitos adversos , Idoso , Antiulcerosos/efeitos adversos , Antagonistas dos Receptores H2 da Histamina/administração & dosagem , Humanos , Deficiência de Magnésio/sangue , Deficiência de Magnésio/tratamento farmacológico , Masculino , Pantoprazol , Inibidores da Bomba de Prótons/administração & dosagem , Resultado do TratamentoRESUMO
No disponible
Assuntos
Masculino , Idoso , Humanos , Acidentes por Quedas , Fraturas do Fêmur/etiologiaRESUMO
Chronic obstructive pulmonary disease (COPD) is a highly prevalent condition and most epidemiological studies have found that COPD prevalence, morbidity and mortality have increased over the last few years. Recent trials suggest that treatments are improving. Several studies have demonstrated the usefulness of the long-acting inhaled beta-2-agonists. Inhaled glucocorticoids, although unable to alter the progression of COPD, may reduce the frequency of acute exacerbations and health status deterioration in a limited group of patients with COPD. Likewise, these drugs may offer benefits in combination with long-acting inhaled beta-agonists. Finally, a better understanding of the molecular and cellular mechanisms involved in COPD pathogenesis should lead to effective treatments that slow or halt the course of the disease. New classes of agents such as the phosphodiesterase inhibitors are now in development.
Assuntos
Broncodilatadores/uso terapêutico , Doença Pulmonar Obstrutiva Crônica/tratamento farmacológico , HumanosRESUMO
La enfermedad pulmonar obstructiva crónica (EPOC) es un proceso altamente prevalente y la mayoría de los estudios epidemiológicos han puesto de manifiesto que su prevalencia, morbilidad y mortalidad se han incrementado durante los últimos años. Investigaciones recientes sugieren una mejoría en el tratamiento. Así, varios estudios han demostrado la utilidad de los beta-2-agonistas inhalados de larga duración. Los glucocorticoides inhalados, aunque incapaces de alterar la progresión de la EPOC, pueden reducir la frecuencia de las exacerbaciones y mejorar la calidad de vida en un grupo limitado de pacientes. Asimismo, pueden ser beneficiosos en combinación con beta-agonistas de acción prolongada. Finalmente, un mejor conocimiento de los mecanismos moleculares y celulares implicados en la patogénesis de la EPOC debería conducir a tratamientos efectivos para lentificar o detener el curso de la enfermedad. Nuevas clases de estos fármacos, como los inhibidores de la fosfodiesterasa, están en el horizonte (AU)
Assuntos
Humanos , Doença Pulmonar Obstrutiva Crônica , BroncodilatadoresRESUMO
No disponible
Assuntos
Idoso , Masculino , Humanos , Síndrome de Secreção Inadequada de HAD , Carcinoma de Células Pequenas , Neoplasias PulmonaresRESUMO
Epidemiologic studies have shown a steady decrease in the blood lead concentrations in populations from developed countries. This decrease is due to the promulgation of legislative measures designed to reduce sources of environmental lead exposure. As a result, during the last several years, lead poisoning has been reported with a minor frequency. We describe here three patients with chronic lead poisoning owing to chronic ingestion of water contaminated by lead pipes.
Assuntos
Intoxicação por Chumbo/etiologia , Doença Crônica , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
Los estudios epidemiológicos han puesto de manifiesto una disminución progresiva en las concentraciones de plomo en sangre en las poblaciones de países desarrollados. Este descenso en la plumbemia se explica por la puesta en marcha de medidas legislativas encaminadas a disminuir la concentración de plomo medio-ambiental. Como resultado, la intoxicación por plomo se ha descrito con una menor frecuencia en los últimos años. Presentamos tres pacientes con intoxicación crónica por plomo debida al uso en la alimentación de agua contaminada por tuberías de plomo. (AU)
